Lipedema and Dercum’s disease: A New Application of Bioimpedance

Lipedema and Dercum’s disease (DD) are incompletely characterized adipose tissue diseases, and objective measures of disease profiles are needed to aid in differential diagnosis. We hypothesized that fluid properties, quantified as tissue water bioimpedance in the upper and lower extremities, differ regionally between these conditions.

Bioimpedance spectroscopy is a noninvasive portable modality to assess tissue water, and this device is available in both specialized and nonspecialized centers. These findings support that regional bioimpedance measures may help to distinguish lipedema from DD, as well as to identify early stages of lipedema.

Rachelle Crescenzi, Paula M.C. Donahue, Sandra Weakley, Maria Garza, Manus J. Donahue, and Karen L. Herbst.Lymphatic Research and Biology.

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