Category Archives: Uncategorized

Widespread painful nodules in a patient with rheumatoid arthritis

A 60-year-old woman affected by rheumatoid arthritis (RA) reported a 12-month history of progressive growth of multiple, painful and symmetrically distributed subcutaneous nodules affecting forearms, thighs and lower back. In the last months the size and the number of nodularities markedly increased, most recently with the appearance of a new lump every other week. These …

Continue reading

Prominent neurological involvement in Dercum disease

Prominent neurological involvement in Dercum disease (Abstract not provided, article behind paywall) http://link.springer.com/article/10.1007/s00415-017-8415-1

Continue reading

Case Report

52 year old obese postmenopausal female presented with complaints of multiple painful lumps over the legs and thighs of 2 years days duration. Clinical examination revealed multiple tender plaques and nodules over both the legs and thighs of different sizes. Biopsy suggestive of lipoma. These features were diagnostic of a rare lipomatosis, dercum’s disease. https://www.omicsgroup.org/journals/dercums-diseaseadiposis-dolorosa-2376-0427-1000252.pdf

Continue reading

Differentiating lipedema and Dercum’s disease

K. Beltran and K. L. Herbst Abstract BACKGROUND: People with lipedema or Dercum’s disease (DD) can have a similar distribution of excess painful nodular subcutaneous adipose tissue (SAT) making them difficult to differentiate. METHODS: Case series of 94 patients with DD, 160 with lipedema and 18 with both diagnoses (Lip+DD) from a single clinic in an …

Continue reading

Mixed generalized/juxta-articular form of Dercum’s disease

Dercum’s disease is a rare disorder with subcutaneous formation of fatty tissue (lipomas) with symptoms of pain, fatigue, stiffness, weakness and in some cases arthritis. Differential diagnosis excluded fibromyalgia, benign symmetric lipomatosis, lipedema, adenolipomatosis, and panniculitis. Dercum’s disease appears in nodular, generalized and juxta-articular forms. In this short report, we report a patient with mixed …

Continue reading

Lipedema: diagnostic and management challenges

Lipedema is an uncommon disorder characterized by localized adiposity of the lower extremities, often occurring in females with a family history of the condition. The adiposity extends from hips to ankles and is typically unresponsive to weight loss. It is important to distinguish Dercum’s disease (adiposis dolorosa) from lipedema, which is characterized by multiple painful …

Continue reading

DERCUM’S DISEASE: AN OVERVIEW OF CLASSIFICATION, CLINICALPRESENTATION, DIAGNOSTIC CRITERIA AND MANAGEMENT

Dercum’s disease is a rare disorder described by generalized obesity with painful adipose tissue. The clinical symptoms presented were multiple painful fatty masses, fatiguablity, swelling of fingers, morning stiffness, cognitive dysfunction, headache, anxiety, rapid heartbeat, shortness of breath, bloating, constipation, easy bruisability, joint aches, muscle aches, mood swing, delirium and dementia. Dercum’s disease affects women …

Continue reading

Rapid Weight Gain

Rapid Weight Gain: A Common Presentation of Adipose Tissue Disorders Weight gain has long been assumed to be a consequence of impaired energy balance due to poor feeding habits and low physical activity. We examined 40 patients who were referred for rapid weight gain or difficulty losing weight without obvious endocrine or non-endocrine causes. Most …

Continue reading

Imaging findings of adiposis dolorosa vs. massive localized lymphedema

Imaging findings of adiposis dolorosa and massive localized lymphedema overlap, as do the symptoms and pathological features. Due to the mass-like engorgement of the soft tissues and pain, patients will often undergo imaging to exclude neoplasm or infection. Knowledge of these conditions and the characteristic imaging findings is important to prevent unnecessary biopsy and misdiagnosis. …

Continue reading

Abnormal Lymphatic Phenotype

An abnormal lymphatic phenotype is associated with subcutaneous adipose tissue deposits in three women with Dercum’s disease. Disclosure: Drs. Fife, Maus, Rasmussen and Sevick-Muraca are listed as inventors on patents related to near-infrared fluorescence lymphatic imaging. Drs. Rasmussen and Sevick-Muraca may receive financial benefit from NIRF Imaging, Inc. a UTHSCH start-up company seeking to commercialize …

Continue reading

MRI and ultrasound appearances

Adiposis dolorosa (Dercum’s disease): MRI and ultrasound appearances http://www.clinicalradiologyonline.net/article/PIIS0009926013001992/abstract

Continue reading