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Localized Nodular Adiposis Dolorosa – Case Study

A 58-year-old female with no previous medical history presented with a 10-year history of recurrent bilateral metacarpophalangeal and proximal interphalangeal joint pain and inflammation, associated with morning stiffness. Early in the course of her disease, she presented to a primary care clinic but did not followed-up due to economic reasons. At the time of this …

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Lipedema and Dercum’s disease: A New Application of Bioimpedance

Lipedema and Dercum’s disease (DD) are incompletely characterized adipose tissue diseases, and objective measures of disease profiles are needed to aid in differential diagnosis. We hypothesized that fluid properties, quantified as tissue water bioimpedance in the upper and lower extremities, differ regionally between these conditions. Bioimpedance spectroscopy is a noninvasive portable modality to assess tissue …

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A case report of lipedema with acute bilateral lower limb ischemia

Lipedema is an uncommon disorder characterized by localized adiposity of the lower extremities, often occurring in females with a family history of this condition. It is described as “adiposis dolorosa” or painful fat and is related to the more extreme adipose tissue disorder, Dercum’s disease. This is a case study suggesting lipedema with associated morbid …

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Dercum’s Disease – Journal Article

Abstract – Dercum’s disease is a rare disease, which mainly affects women and has an unknown prevalence and aetiology. The disease is characterised by generalised obesity and more than three-month painful subcutaneous adipose tissue not responding to usual pain treatment. A suggested classification of the disease includes four types: generalised diffuse, generalised nodular, localised nodular …

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Concurrent pulmonary embolism in female monozygotic twins affected by Dercum’s disease

“We describe a pair of female monozygotic twins with Dercum’s disease (DD) who presented simultaneously with unprovoked pulmonary emboli. Several genetic determinants have been associated with venous thromboembolism (VTE) but the overall influence of genetic factors is unknown. As yet there is no published evidence to support an increase in the risk of VTE in …

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