Tag Archives: dolorosa

Genetic syndromes with localized subcutaneous fat tissue accumulation

Summary. Syndromes with localized accumulation of subcutaneous fatty tissue belong to a group of genetically and phenotypically heterogeneous disorders. These diseases may show some common signs, such as nodular fat, symmetrical fat masses, obesity, fatigue, lymphedema and symmetrical lipomas (painful or otherwise). Other symptoms may be specific for the different clinical entities, enabling correct differential …

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Localized Nodular Adiposis Dolorosa – Case Study

A 58-year-old female with no previous medical history presented with a 10-year history of recurrent bilateral metacarpophalangeal and proximal interphalangeal joint pain and inflammation, associated with morning stiffness. Early in the course of her disease, she presented to a primary care clinic but did not followed-up due to economic reasons. At the time of this …

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Low dose d-amphetamine induced regression of liver fat deposits in Dercum disease

Clinical Significance • D-amphetamine anecdotally improves the painful fat/lymphatic disorder, Dercum’s disease. • Two patients with Dercum’s disease were treated with d-amphetamine to improve lymphatic function through the sympathetic nervous system. • Both patients lost weight, and fatty liver in a man and liver lipomas in a woman resolved in less than a year on …

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Widespread painful nodules in a patient with rheumatoid arthritis

A 60-year-old woman affected by rheumatoid arthritis (RA) reported a 12-month history of progressive growth of multiple, painful and symmetrically distributed subcutaneous nodules affecting forearms, thighs and lower back. In the last months the size and the number of nodularities markedly increased, most recently with the appearance of a new lump every other week. These …

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***DERCUM’S DISEASE: AN OVERVIEW OF CLASSIFICATION, CLINICALPRESENTATION, DIAGNOSTIC CRITERIA AND MANAGEMENT

Dercum’s disease is a rare disorder described by generalized obesity with painful adipose tissue. The clinical symptoms presented were multiple painful fatty masses, fatiguablity, swelling of fingers, morning stiffness, cognitive dysfunction, headache, anxiety, rapid heartbeat, shortness of breath, bloating, constipation, easy bruisability, joint aches, muscle aches, mood swing, delirium and dementia. Dercum’s disease affects women …

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