Dercum’s Disease: A Rare Disease of Painful Fatty Lumps
Case study, 27 year old male.
Full text with photos;
JUXTA-ARTICULAR ADIPOSIS DOLOROSA IN LIPEDEMA PATIENTS
Article from Georgian Med News
“Both lipedema and juxta-articular adiposis dolorsa are painful disorders of subcutaneous adipose tissue. We investigated 297 female patients with lipedema treated at our department for the presence of juxta-articular adiposis dolorsa. Occurrence of both disorders was identified in 4.4% of lipedema patients. The common presence of both disorders was observed only in more advanced lipedema (grade II and III). Juxta-articular adiposis dolorosa of the knees is seen exclusively on the inner knees, and it presents neither bruising nor creases or hypothermia. Choices of surgical treatment are either microcannula liposuction or dermolipectomy. Recurrences have not been observed.”
https://pubmed.ncbi.nlm.nih.gov/34511435/
https://academic-accelerator.com/Impact-Factor-IF/Georgian-medical-news
Lurking Under the Surface: Dercum’s Disease
This is a case study that begins with a good description of Dercum’s disease.
https://www.cureus.com/articles/64912-lurking-under-the-surface-dercums-disease
Metabolic and immunological phenotype of rare lipomatoses: Dercum’s disease and Roch-Leri mesosomatic lipomatosis
DD and LMS show a common background of obesity and metabolic phenotype, but a distinct immunohematological profile characterized by a higher number of basophils in DD patients, an inflammatory profile that could contribute to pain. T lymphocyte depletion was present in LMS. These findings could offer specific therapeutic opportunities, especially for painful DD.
Full Text: https://ojrd.biomedcentral.com/articles/10.1186/s13023-021-01920-3
RZL-012, a New Fat Dissolving Molecule, Tested in Dercum’s Disease Patients
The results from this research are behind a paywall.
Dercum's Disease Research 