Category Archives: Causes
Infections Preceding the Development of Dercum disease
This case series calls attention to the presence of lipomas occurring after infections including Lyme disease, histoplasmosis and coccidioidomycosis. Studies examining larger populations with infections are needed, and evaluation of adipose tissue and the lymphatic system in animal models of infections may provide evidence further connecting infection and changes in fat tissue consistent with lipomas. …
Identification of somatic alterations in lipoma using whole exome sequencing
Until now, reason for lipoma occurrence not been identified. We performed whole exome sequencing to define the mutational spectrum in ten lipoma patients along with their matching control samples. We presented genomic insight into the development of lipomas, the most common benign tumor of soft tissue. Our analysis identified 412 somatic variants including missense mutations, …
Genetic syndromes with localized subcutaneous fat tissue accumulation
Summary. Syndromes with localized accumulation of subcutaneous fatty tissue belong to a group of genetically and phenotypically heterogeneous disorders. These diseases may show some common signs, such as nodular fat, symmetrical fat masses, obesity, fatigue, lymphedema and symmetrical lipomas (painful or otherwise). Other symptoms may be specific for the different clinical entities, enabling correct differential …
A STUDY OF DERMATOLOGICAL PROBLEMS FACED BY OBESE PATIENTS:
This study of dermatological problems faced by obese patients lists adiposis dolorosa as a “skin manifestation”. Adiposis dolorosa is included in a list of dermatological complications of obesity. “Obesity is said to cause…adiposis dolorosa.” Please remember that the administrators of this website are simply providing links to research as it is published. If you want …
Trauma-induced adiposis dolorosa (Dercum’s disease)
Summary We present a case of a 39-year-old man who presented with chronic bilateral upper extremity pain associated with innumerable angiomyolipomas that developed 5 years after a motor vehicle accident involving his upper extremities. Our case notes the rare nature of painful adipose tissue deposits and the diagnostic challenges. BMJ Case Reports 2018; doi:10.1136/bcr-2017-223869 http://casereports.bmj.com/content/2018/bcr-2017-223869.abstract
Dercum's Disease Research 